Friday, March 30, 2012

Gout vs Pseudogout

  1. Crystals:
    • Gout = NEGATIVELY birefringent (uric acid)
    • Pseudogout = POSITIVELY birefringent (calcium pyrophosphate)
  2. Treatment:
    • Gout:
      • Acute attack: 1st line NSAID's except aspirin; 2nd line COLCHICINE
      • Chronic: URICOSURICO agents (Never use in acute crisis)

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